The paper by lab members was published in the highly rated journal Placenta
In the article “Modeling Preeclampsia: From 2D Cultures to Placenta-on-a-Chip Technologies,” Russian scientists have presented an overview of modern cellular models of preeclampsia—a dangerous pregnancy complication. The study covers two-dimensional and three-dimensional cultures, as well as advanced placenta-on-a-chip microfluidic technologies, allowing the examination of pathological mechanisms at the cellular level. The paper highlights the potential of CRISPR-Cas9 and personalized models for developing new diagnostic and therapeutic methods for preeclampsia. These advancements open prospects for more precise early diagnosis of preeclampsia and the creation of effective treatment strategies.
Evgeny Knyazev Presented the Laboratory’s Research Results at the IV Congress of Young Scientists
During the session “Microfluidic Technologies: Will Organ-on-Chip Replace In Vivo Studies?”, Evgeny Knyazev presented the laboratory’s research projects, including:
Development of an in vitro intestine-on-a-chip model with physiologic permeability characteristics;
RSF grant project: Microfluidic placenta-on-a-chip model for the study of preeclampsia.
Laboratory Staff Participated in a Scientific Conference Organized by the Faculty of Biology and Biotechnology
Four presentations were delivered, focusing on modeling the microenvironment of various body structures and the practical application of these models for studying pathological processes
The research from the laboratory was presented at the second Drug Developers Summit "Sirius.Biotech"
As part of the special session "Study of Safety and Biomarkers of New Drugs," a report was given on "The Use of the 'Human-on-a-Chip' Platform in Drug Development"