Established in 2020, the Laboratory of Molecular Physiology studies the role of microRNA isoforms in the pathogenesis of intestinal diseases and develops new therapeutic approaches to intestinal condition treatment using microRNA isoforms. We collaborate with the National Medical Research Radiological Center, the Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and University Medical Center Hamburg-Eppendorf.
The Laboratory was created to further priority areas of scientific research of the Faculty of Biology and Biotechnology in the field of molecular physiology, which are urgently needed for the development of a modern high-tech methods of diagnostics, prevention, and monitoring of treatment of various diseases in the transition to personalized medicine.
On November 29, 2022, a workshop on 'Modeling the biogenesis of SARS-CoV-2' was held at the Laboratory of Molecular Physiology
II All-Russian Conference with International Participation 'Mathematics in Medicine' was held in Vladivostok From October 10 to October 15, 2022. Laboratory members D.V. Alekseev, A.V. Galatenko and V.M. Staroverov with co-authors from the Faculty of Mechanics and Mathematics of Lomonosov Moscow State University presented a talk 'A mathematical model of COVID-19 infection dynamics'.
On November 22, 2022, a workshop was held at the Laboratory of Molecular Physiology on 'The Relationship of MicroRNA Expression in the Intestinal Epithelium with the Expression of (+)RNA of Viruses'.
On November 15, 2022, the Laboratory of Molecular Physiology held a scientific seminar titled 'The influence of SARS-CoV-2 VOC Omicron mutations on the spectrum of high-affinity peptides in the Moscow population'
At the meeting, the head of the laboratory Galatenko A. V., leading researchers Staroverov V. M. and Alekseev D. V. reviewed their new work on mathematical modeling of infection.
Laboratory of Molecular Physiology HSE University together with colleagues from the Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow State University, the Moscow Center for Fundamental and Applied Mathematics, and the Institute of Nanotechnologies for Microelectronics of the Russian Academy of Sciences have developed ExhauFS, a tool that allows you to conduct an exhaustive search for feature subsets to build the most powerful cancer survival classification and regression models.
The 5th Sechenov International Biomedical Summit (SIBS - 2021) was held on November 9-10, 2021 at FSAU VO Sechenov Russian Ministry of Health (Sechenov University). It is one of the most authoritative forums in the country in the field of advanced bioengineering, regenerative and personalized medicine.
25th International Conference on Research in Computational Molecular Biology (RECOMB 2021) was held online on August 29th - September 2nd. Staff of the Faculty of Biology and Biotechnology - Stepan Nersisyan, Alexey Galatenko, Diana Maltseva and Alexander Tonevitsky participated in a poster session with the report 'miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence'
Alexander G. Tonevitsky, Leading Research Fellow of the International Laboratory of Microphysiological Systems, took part at the 11th World Congress on Alternatives and Use of Animals in Natural Sciences (WC11)
HSE University researchers assessed the effectiveness of the T-cell immune response to 11 variants of SARS-CoV-2. Their findings have been published in Nucleic Acids Research.