About the Laboratory

The laboratory was established with a primary aim to invigorate the pivotal areas of scientific exploration within the Faculty of Biology and Biotechnology, focusing on the expanding field of molecular physiology. This emphasis aligns with the pressing demand within modern, high-tech healthcare for advancements in diagnosing, preventing, and monitoring various diseases, particularly in the context of transitioning towards personalized medicine.

The convergence of rapid diagnostic advancements and information technology has transformed biology and medicine into information-driven industries, generating extensive databases of human health through cutting-edge genomic, post-genomic, and other precise molecular technologies. Thus, a fundamental aspect of the laboratory's mission involves fostering an effective dissemination mechanism for novel research approaches and result interpretation within the realms of biology and medicine, both in professional and educational settings.

Key focus areas encompass:

• Uncovering novel molecular mechanisms explaining disease pathogenesis.
• Creating in vitro 'organ-on-a-chip' models, such as microfluidic models mimicking human gut, placenta, and other vital organs, facilitating the simulation of human tissue and organ components.
• Developing biological test systems that replicate the functionality of human organs and tissues.
• Pioneering innovative approaches utilizing microRNAs and their isoforms to address organ dysfunction, thus paving the way for potential therapeutic interventions.
• Engaging in systems biology research, handling and interpreting vast datasets effectively.

The laboratory thrives on international collaborations, leveraging partnerships to access unique data, secure additional funding from external sources, and publish research outcomes in esteemed articles. Furthermore, the laboratory extends invitations to renowned Russian research institutions that possess significant standing in the global biological and medical science domains, fostering robust international connections and collaborations.

Partners

Department of Translational Oncology, National Medical Research Center for Radiology

Laboratory of microfluidic technologies for biomedicine, Shemyakin-Ovchinnikov Institute of bioorganic chemistry RAS

Department of Obstetrics and Gynecology, Sechenov University

Institute of Anatomy and Experimental Morphology, University Hospital Hamburg-Eppendorf.

Educational activities

The Laboratory actively involves Bachelor's, Master's, and graduate students from the Faculty of Biology and Biotechnology at the HSE University. This engagement provides students with invaluable hands-on experience in laboratory methods and principles of scientific inquiry through real-world applied research in the fields of biology and medicine.