Researchers of Molecular Physiology Laboratory Optimize Microfluidic Chip Composition for Long-Term Organ-on-a-Chip Cultivation
Applied Biochemistry and Microbiology has published an article by researchers from the Molecular Physiology Laboratory at HSE University and the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, dedicated to optimizing the gas permeability of polydimethylsiloxane (PDMS)—a material widely used for manufacturing microfluidic chips in organ-on-a-chip systems.
HSE Researchers Present Organ-on-a-Chip Models for Studying Preeclampsia and Inflammatory Bowel Disease at the III International Forum of Genomic and Biomedical Technologies
On December 4, 2025, Evgeny Knyazev, Head of the Molecular Physiology Laboratory at HSE University, delivered a presentation titled "Modeling Preeclampsia and Inflammatory Bowel Diseases Using Placenta-on-a-Chip and Intestine-on-a-Chip Models" at the III International Forum of Genomic and Biomedical Technologies "From Birth to Active Longevity" in Surgut.
HSE Researchers Develop Method to Verify Reliability of Computer-Based Cancer Recurrence Prediction
Research by a collaborative team from HSE University's Faculty of Biology and Biotechnology, Moscow State University, and the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences has been officially published in the international journal Stat. The study addresses a critical challenge in biomedicine: determining whether machine learning algorithms identify genuine biological patterns or merely overfit to random noise in data.
Joint Study by Molecular Physiology Laboratory and Kulakov National Medical Research Center Published in RUDN Journal of Medicine
A research article by a collaborative team from the Molecular Physiology Laboratory at HSE University and the V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology has been published in a leading medical journal. The study presents the first comparative analysis of immune-associated gene expression in classical blood monocytes from women with preeclampsia compared to physiological pregnancy.
HSE Researchers Identify Molecular Markers of Hypoxia in Preeclampsia
Researchers at the Molecular Physiology Laboratory of HSE University presented results of a multidisciplinary investigation into preeclampsia, correlating single-cell sequencing data from placental tissue in early-onset preeclampsia with experimental hypoxia induction in cell models. For the first time, gene expression profiles in diseased placental samples were directly compared to the molecular response of trophoblasts subjected to chemical hypoxia induction using a novel oxyquinoline derivative.
Article on Molecular Physiology Laboratory Developments Published in "HSE University Science News"
The official HSE University website has published an article titled "New Models for Disease Research: From Petri Dish to Organs-on-a-Chip," focusing on the work of the Molecular Physiology Laboratory at the Faculty of Biology and Biotechnology in developing innovative approaches to organ-on-chip modeling and researching preeclampsia — one of the most dangerous pregnancy complications.
Molecular Physiology Laboratory and HSE.Tech Release Video on Biochips and Organs-on-a-Chip in “±10 Minutes.HSE.Tech” Series
The Molecular Physiology Laboratory at HSE University, together with the HSE.Tech portal, has produced a two-part video for the “±10 Minutes.HSE.Tech” series. The episodes explain organ-on-a-chip technology, its operating principles, medical applications, and the prospects of biochips for personalized therapy and artificial organs.
Laboratory Staff Member Presented Report at Conference "Experimental and Informational Approaches to Pathological States Research"
On June 17, the Faculty of Biology and Biotechnology at HSE University hosted the conference "Experimental and Informational Approaches to Pathological States Research." The event featured participation from a laboratory staff member, Olga Chebotareva, a third-year graduate student in Molecular Biology, who presented the report "Microfluidic Modeling of Trophoblast Invasion: An Experimental Approach to Studying Preeclampsia Pathogenesis."
Head of HSE University Laboratory Evgeny Knyazev Completed Management Talent Pool Program at Senezh Management Workshop
The fourth module of the strategic-level Management Talent Pool Development Program in Science, Technology, and Higher Education concluded at the Senezh Management Workshop. Among the 82 participants who received certificates of professional development was Evgeny Knyazev, Head of the Molecular Physiology Laboratory at the Faculty of Biology and Biotechnology, HSE University.
Head of HSE University Laboratory Evgeny Knyazev Participates in Strategic Module of Management Talent Pool Program in St. Petersburg
The third module of the strategic-level Management Talent Pool Development Program in Science, Technology, and Higher Education concluded at the Empress Catherine II St. Petersburg Mining University. Among the participants was Evgeny Knyazev, Head of the Molecular Physiology Laboratory at the Faculty of Biology and Biotechnology, HSE University
Advanced Training for Science and Technology Leaders: Second Module of RANEPA’s Presidential Academy Program
The second module of the Management Talent Pool Development Program in Science, Technology, and Higher Education concluded at the Presidential Academy of the Russian Academy of National Economy and Public Administration (RANEPA). The event brought together 85 leaders from scientific organizations, laboratory heads, technology company representatives, and leading Russian universities, including Evgeny Knyazev, Head of the Molecular Physiology Laboratory at HSE University
Head of the Molecular Physiology Laboratory at HSE University Joins National Management Talent Pool
Evgeny Knyazev Begins Training in the Fourth Cohort of the Management Talent Pool Development Program in Science, Technology, and Higher Education at Sirius Federal Territory