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Regular version of the site

International Laboratory of Microphysiological Systems

The laboratory is developing a new method of personalized drug therapy for cancer patients, which includes establishment of a three-dimensional culture of tumor organoids, followed by a personalized test of chemotherapeutic and targeted drugs to determine the most effective therapy for each individual patient.

We maintain cooperation with National Medical Research Radiological Center, Shemyakin–Ovchinnikov Institute of bioorganic chemistry RAS, Scientific and Technical Center BioClinicum and University Medical Center Hamburg-Eppendorf.


CD24 expression level as a prognostic marker of survival in colorectal cancer

Researchers of the International Laboratory of Microphysiological Systems of the Faculty of Biology and Biotechnology (HSE University), in collaboration with the Laboratory of Molecular Physiology of the Faculty of Biology and Biotechnology (HSE University), as well as German colleagues from the Institute of Anatomy and Experimental Morphology (Hamburg) and the Institute of Pathology (Göttingen), found an association between low expression of the CD24 protein in patients with colorectal cancer and a decrease in patient survival rate.

The article «Specificity of viscumin revised. As probed with a printed glycan array» accepted to Biochimie journal

An article by the staff of the International Laboratory of Microphysiological Systems and collaborators from the Institute of Bioorganic Chemistry of the Russian Academy of Sciences «Specificity of viscumin revised. As probed with a printed glycan array» accepted for publishing in Biochimie journal.

Seminar: gene overexpressionSeminar

On June 24, 2022, the International Laboratory of Microphysiological Systems hosted a joint seminar with the Laboratory for Research on the Molecular Mechanisms of Longevity, dedicated to the issue of miRNA overexpression in human cells, a process that leads to an excess amount of transcript produced by the genome.

Illustration for news: HSE University Launches Third Mirror Laboratories Competition

HSE University Launches Third Mirror Laboratories Competition

The competition is open to HSE University research units planning to conduct joint projects with academic institutions, research organisations and state academic centres of the Russian Federation. Applications are open until May 20, 2022.

Illustration for news: HSE University to Establish Four New International Labs

HSE University to Establish Four New International Labs

Two international laboratories will be created at the HSE University Institute of Electronics and Mathematics, one at the Faculty of Geography and Geoinformation Technology, and one at the Faculty of Biology and Biotechnology. The four projects were selected from a total of 17 applications.

Illustration for news: Members of the International Laboratory of Microphysiological Systems took part in SIBS-2021

Members of the International Laboratory of Microphysiological Systems took part in SIBS-2021

The 5th Sechenov International Biomedical Summit (SIBS - 2021) was held on November 9-10, 2021 at FSAU VO Sechenov Russian Ministry of Health (Sechenov University). It is one of the most authoritative forums in the country in the field of advanced bioengineering, regenerative and personalized medicine.

Illustration for news: Members of the International Laboratory of Microphysiological Systems and the Laboratory of Molecular Physiology participated in RECOMB 2021

Members of the International Laboratory of Microphysiological Systems and the Laboratory of Molecular Physiology participated in RECOMB 2021

25th International Conference on Research in Computational Molecular Biology (RECOMB 2021) was held online on August 29th - September 2nd. Staff of the Faculty of Biology and Biotechnology - Stepan Nersisyan, Alexey Galatenko, Diana Maltseva and Alexander Tonevitsky participated in a poster session with the report «miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence»

Illustration for news: The International Laboratory of Microphysiological Systems at the 11th World Congress on Alternatives and Uses of Animals in Natural Sciences (WC11)

The International Laboratory of Microphysiological Systems at the 11th World Congress on Alternatives and Uses of Animals in Natural Sciences (WC11)

Alexander G. Tonevitsky, Leading Research Fellow of the International Laboratory of Microphysiological Systems, took part at the 11th World Congress on Alternatives and Use of Animals in Natural Sciences (WC11)

Illustration for news: HSE University Invites Leading Researchers to Experimental Research Laboratory Competition

HSE University Invites Leading Researchers to Experimental Research Laboratory Competition

HSE University has announced an open project competition to create experimental research laboratories in the natural sciences. The competition is open to research projects in the fields of biophotonics and ageing (biology, physiology, biomedicine, biostatistics, and bioinformatics.)

Illustration for news: Russian Scientists Investigate the Immune Response to SARS-CoV-2 Variants

Russian Scientists Investigate the Immune Response to SARS-CoV-2 Variants

HSE University researchers assessed the effectiveness of the T-cell immune response to 11 variants of SARS-CoV-2. Their findings have been published in Nucleic Acids Research.