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Tag "Colorectal cancer"

Illustration for news: Single‑cell sequencing analysis reveals differences in the microenvironment of left‑ and right‑sided colorectal cancer

Single‑cell sequencing analysis reveals differences in the microenvironment of left‑ and right‑sided colorectal cancer

Researchers from the International Laboratory of Microphysiological Systems have presented a review devoted to single‑cell analysis of colorectal cancer. The article systematises current data obtained using single‑cell RNA‑sequencing technologies, with a particular focus on the fundamental differences between left‑ and right‑sided tumours

Illustration for news: MicroRNAs Are Involved in Regulating Colorectal Cancer Metastasis via the CD44 Receptor

MicroRNAs Are Involved in Regulating Colorectal Cancer Metastasis via the CD44 Receptor

Knockdown of CD44 in colorectal cancer tumours alters the expression of microRNAs and their targets involved in epithelial–mesenchymal transition and the Notch signalling pathway, both of which are associated with tumour metastasis