Key Stages of Western Blotting Automated in the Laboratory
The International Laboratory of Microphysiological Systems has implemented an automated system for preparing polyacrylamide gels of various compositions, as well as a robotic workstation for immunoblotting, into its research workflow
Single‑cell sequencing analysis reveals differences in the microenvironment of left‑ and right‑sided colorectal cancer
Researchers from the International Laboratory of Microphysiological Systems have presented a review devoted to single‑cell analysis of colorectal cancer. The article systematises current data obtained using single‑cell RNA‑sequencing technologies, with a particular focus on the fundamental differences between left‑ and right‑sided tumours
Interview with the Head of the International Laboratory of Microphysiological Systems, Diana Maltseva, Published
Diana Vasilievna spoke about the laboratory's work to Vyshka.Glavnoe
Researcher of the International Laboratory of Microphysiological Systems Takes Part in the International Conference for Young Scientists “Genetic Technologies in Biomedicine”
An employee of the International Laboratory of Microphysiological Systems took part in the International Conference for Young Scientists “Genetic Technologies in Biomedicine”
Postgraduate of the International Laboratory of Microphysiological Systems Takes Part in HSE University’s “Young Scientists” Programme
The International Laboratory of Microphysiological Systems is pleased to share an interview given by junior research fellow Maria Yanova as part of the “Young Scientists” project. In this inspiring piece, Maria tells her own story in science
%20(4).jpg "MicroRNAs Are Involved in Regulating Colorectal Cancer Metastasis via the CD44 Receptor")
MicroRNAs Are Involved in Regulating Colorectal Cancer Metastasis via the CD44 Receptor
Knockdown of CD44 in colorectal cancer tumours alters the expression of microRNAs and their targets involved in epithelial–mesenchymal transition and the Notch signalling pathway, both of which are associated with tumour metastasis
The staff of the International Laboratory participated in the International Scientific Forum
Three poster presentations were presented with the latest data of scientific research conducted in the laboratory
Anna Shestakova from the laboratory participated in the 12th International Mycological Congress (IMC12)
The Congress was held from 11-15 August 2024 in Maastricht, the Netherlands
The International Laboratory of Microphysiological Systems organized and conducted a conference with international participation at the Faculty of Biology and Biotechnology of the National Research University Higher School of Economics
The conference was held on 11 July 2024
_v3.jpg "The manuscript of the Laboratory of Microphysiological Systems team has been accepted for publication")
The manuscript of the Laboratory of Microphysiological Systems team has been accepted for publication
Our results show that the design of shRNA affects its processing by RNase-III Dicer and can result in the generation of undesirable 5'-isoforms of miRNA/siRNA encoded within the shRNA. This effect is especially significant for miRNA/siRNA longer than 19 nt.