Article "Biology-inspired Microphysiological Systems to Advance Patient Benefit and Animal Welfare in Drug Development" is published in ALTEX
Joint scientific work is published by Alexander Tonevitsky, the Dean of Faculty of Biology and Biotechnology of the Higher School of Economics and foreign colleagues
In this work 46 leading experts from all stakeholders – academia, MPS supplier industry, pharmaceutical and consumer products industries, and leading regulatory agencies – worldwide have analyzed existing challenges and hurdles along the MPS-based assay life cycle. It was identified that the major challenge for industrial adoption of MPS researsh implementation by end users is a communication gap between stakeholders. This report elaborates on these findings in detail and summarizes solutions how to overcome the roadblocks. Also it provides recommendations and a roadmap towards further laboratory animal reduction in drug development with the use of microphysiological systems.