HSE Researchers Identify Molecular Markers of Hypoxia in Preeclampsia
Researchers at the Molecular Physiology Laboratory of HSE University presented results of a multidisciplinary investigation into preeclampsia, correlating single-cell sequencing data from placental tissue in early-onset preeclampsia with experimental hypoxia induction in cell models. For the first time, gene expression profiles in diseased placental samples were directly compared to the molecular response of trophoblasts subjected to chemical hypoxia induction using a novel oxyquinoline derivative.
Research & Expertisediscussionspublicationsresearch projectshypoxiamicroRNAOxyquinoline derivativePreeclampsiaSingle-cell sequencing
26 September